Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Monoglyceride lipase' and Ligand = 'BDBM280574'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Mus musculus (mouse))	BDBM280574 (BDBM280666 | US10030020, Example 119 | US10781211,...) Show SMILES OC(=O)C1CCN(CC1)c1cc(ccc1CN1CCC2(C1)CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C26H30F9N3O4/c27-24(28,29)18-2-1-17(19(13-18)37-8-3-16(4-9-37)20(39)40)14-36-10-5-23(15-36)6-11-38(12-7-23)22(41)42-21(25(30,31)32)26(33,34)35/h1-2,13,16,21H,3-12,14-15H2,(H,39,40)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM280574 (BDBM280666 | US10030020, Example 119 | US10781211,...) Show SMILES OC(=O)C1CCN(CC1)c1cc(ccc1CN1CCC2(C1)CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C26H30F9N3O4/c27-24(28,29)18-2-1-17(19(13-18)37-8-3-16(4-9-37)20(39)40)14-36-10-5-23(15-36)6-11-38(12-7-23)22(41)42-21(25(30,31)32)26(33,34)35/h1-2,13,16,21H,3-12,14-15H2,(H,39,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	25
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0-2.0 mg/mL total protein concentration) were preincubated with varying...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM280574 (BDBM280666 | US10030020, Example 119 | US10781211,...) Show SMILES OC(=O)C1CCN(CC1)c1cc(ccc1CN1CCC2(C1)CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C26H30F9N3O4/c27-24(28,29)18-2-1-17(19(13-18)37-8-3-16(4-9-37)20(39)40)14-36-10-5-23(15-36)6-11-38(12-7-23)22(41)42-21(25(30,31)32)26(33,34)35/h1-2,13,16,21H,3-12,14-15H2,(H,39,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description Human: Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0-2.0 mg/mL total protein concentration) were preincubated with ...				US Patent US10781211 (2020) BindingDB Entry DOI: 10.7270/Q2RX9G56
					More data for this Ligand-Target Pair
Monoglyceride lipase (Mus musculus (mouse))	BDBM280574 (BDBM280666 | US10030020, Example 119 | US10781211,...) Show SMILES OC(=O)C1CCN(CC1)c1cc(ccc1CN1CCC2(C1)CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C26H30F9N3O4/c27-24(28,29)18-2-1-17(19(13-18)37-8-3-16(4-9-37)20(39)40)14-36-10-5-23(15-36)6-11-38(12-7-23)22(41)42-21(25(30,31)32)26(33,34)35/h1-2,13,16,21H,3-12,14-15H2,(H,39,40)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020) BindingDB Entry DOI: 10.7270/Q2RX9G56
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM280574 (BDBM280666 | US10030020, Example 119 | US10781211,...) Show SMILES OC(=O)C1CCN(CC1)c1cc(ccc1CN1CCC2(C1)CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C26H30F9N3O4/c27-24(28,29)18-2-1-17(19(13-18)37-8-3-16(4-9-37)20(39)40)14-36-10-5-23(15-36)6-11-38(12-7-23)22(41)42-21(25(30,31)32)26(33,34)35/h1-2,13,16,21H,3-12,14-15H2,(H,39,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	25
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0-2.0 mg/mL total protein concentration) were preincubated with varying...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair