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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Motilin receptor' and Ligand = 'BDBM50214256'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Motilin receptor


(Homo sapiens (Human))		BDBM50214256
PNG
((5R,8R,11S)-5-[(3-fluorophenyl)methyl]-8-(propan-2...)
Show SMILES CC(C)[C@H]1NC(=O)[C@@H](Cc2cccc(F)c2)NCCOc2ccccc2CCCNC(=O)[C@H](Cc2cscn2)NC1=O
Show InChI InChI=1S/C31H38FN5O4S/c1-20(2)28-31(40)36-26(17-24-18-42-19-35-24)29(38)34-12-6-9-22-8-3-4-11-27(22)41-14-13-33-25(30(39)37-28)16-21-7-5-10-23(32)15-21/h3-5,7-8,10-11,15,18-20,25-26,28,33H,6,9,12-14,16-17H2,1-2H3,(H,34,38)(H,36,40)(H,37,39)/t25-,26+,28-/m1/s1
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 116n/an/an/an/an/an/an/an/a



Tranzyme Pharma Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]-motilin from human motilin receptor expressed in CHO cells

Bioorg Med Chem Lett 17: 4187-90 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.043
BindingDB Entry DOI: 10.7270/Q2GF0T62
More data for this
Ligand-Target Pair