Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Motilin receptor (Homo sapiens (Human)) | BDBM50292978 (CHEMBL489095 | GSK-962040 | N-(3-Fluorophenyl)-1-[...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 970 | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.bmcl.2022.128554 BindingDB Entry DOI: 10.7270/Q2Q81J37 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Motilin receptor (Homo sapiens (Human)) | BDBM50292978 (CHEMBL489095 | GSK-962040 | N-(3-Fluorophenyl)-1-[...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 12.6 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assay | J Med Chem 52: 1180-9 (2009) Article DOI: 10.1021/jm801332q BindingDB Entry DOI: 10.7270/Q208666T | |||||||||||
More data for this Ligand-Target Pair |