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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50058153'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mu-type opioid receptor


(MOUSE)
BDBM50058153
PNG
(7-(5',6'-Benzo-2'-spiroindanyl)oxymorphone | CHEMB...)
Show SMILES CN1CCC23C4Oc5c2c(CC1[C@]3(O)CC1(Cc2cc3ccccc3cc2C1)C4=O)ccc5O |TLB:13:12:8.9.10:1.3.2,THB:7:8:12:1.3.2,0:1:12:8.9.10|
Show InChI InChI=1S/C29H27NO4/c1-30-9-8-28-23-18-6-7-21(31)24(23)34-26(28)25(32)27(15-29(28,33)22(30)12-18)13-19-10-16-4-2-3-5-17(16)11-20(19)14-27/h2-7,10-11,22,26,31,33H,8-9,12-15H2,1H3/t22?,26?,28?,29-/m1/s1
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PC cid
PC sid
UniChem
Article
PubMed
125n/an/an/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
The compound tested for agonistic activity against Opioid receptor mu 1 using [3H]- DAMGO as the radioligand.


J Med Chem 40: 1720-5 (1997)


Article DOI: 10.1021/jm9700880
BindingDB Entry DOI: 10.7270/Q2FB53M9
More data for this
Ligand-Target Pair