Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50097577'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (GUINEA PIG)	BDBM50097577 ((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...) Show SMILES C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)C(=O)Nc1ccccc1 |TLB:8:9:1:14.12.13,15:14:1:9.4.3| Show InChI InChI=1S/C25H30N2O/c1-17-23-15-19-10-11-20(24(28)26-21-6-4-3-5-7-21)14-22(19)25(17,2)12-13-27(23)16-18-8-9-18/h3-7,10-11,14,17-18,23H,8-9,12-13,15-16H2,1-2H3,(H,26,28)/t17-,23?,25-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rensselaer Polytechnic Institute Curated by ChEMBL					Assay Description Binding affinity was determined towards opioid receptor mu1 using [3H]-DAMGO as radioligand				Bioorg Med Chem Lett 13: 1911-4 (2003) BindingDB Entry DOI: 10.7270/Q2FB529V
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50097577 ((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...) Show SMILES C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)C(=O)Nc1ccccc1 |TLB:8:9:1:14.12.13,15:14:1:9.4.3| Show InChI InChI=1S/C25H30N2O/c1-17-23-15-19-10-11-20(24(28)26-21-6-4-3-5-7-21)14-22(19)25(17,2)12-13-27(23)16-18-8-9-18/h3-7,10-11,14,17-18,23H,8-9,12-13,15-16H2,1-2H3,(H,26,28)/t17-,23?,25-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rensselaer Polytechnic Institute Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from Opioid receptor mu 1 of guinea pig brain membranes				Bioorg Med Chem Lett 11: 623-6 (2001) BindingDB Entry DOI: 10.7270/Q2542MVZ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50097577 ((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...) Show SMILES C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)C(=O)Nc1ccccc1 |TLB:8:9:1:14.12.13,15:14:1:9.4.3| Show InChI InChI=1S/C25H30N2O/c1-17-23-15-19-10-11-20(24(28)26-21-6-4-3-5-7-21)14-22(19)25(17,2)12-13-27(23)16-18-8-9-18/h3-7,10-11,14,17-18,23H,8-9,12-13,15-16H2,1-2H3,(H,26,28)/t17-,23?,25-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rensselaer Polytechnic Institute Curated by ChEMBL					Assay Description Antagonist activity against human mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS binding				J Med Chem 49: 5635-9 (2006) Article DOI: 10.1021/jm060278n BindingDB Entry DOI: 10.7270/Q208663G
					More data for this Ligand-Target Pair