Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50130561 ((R)-N-((S)-1-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dime...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Binding affinity towards human cloned Opioid receptor mu 1 using [3H]DAMGO | J Med Chem 46: 3127-37 (2003) Article DOI: 10.1021/jm030094y BindingDB Entry DOI: 10.7270/Q2319WM4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50130561 ((R)-N-((S)-1-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dime...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 775 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Inhibition of [3H]DAMGO binding to Opioid receptor mu 1 of rat brain tissue | J Med Chem 46: 3127-37 (2003) Article DOI: 10.1021/jm030094y BindingDB Entry DOI: 10.7270/Q2319WM4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50130561 ((R)-N-((S)-1-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dime...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 775 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Binding affinity of compound for Opioid receptor mu 1 was determined using [3H]DAMGO as radioligand from rat brain tissue | J Med Chem 47: 1070-3 (2004) Article DOI: 10.1021/jm030467v BindingDB Entry DOI: 10.7270/Q2BV7HC4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50130561 ((R)-N-((S)-1-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dime...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity at human mu opioid receptor assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS binding | Bioorg Med Chem Lett 20: 5847-52 (2010) Article DOI: 10.1016/j.bmcl.2010.07.113 BindingDB Entry DOI: 10.7270/Q23F4PV1 | |||||||||||
More data for this Ligand-Target Pair |