Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50173265'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50173265 (2-[1'-cyclooctylmethyl-2-oxospiro[2,3-dihydro-1H-i...) Show SMILES OC(=O)CN1C(=O)C2(CCN(CC3CCCCCCC3)CC2)c2ccccc12 Show InChI InChI=1S/C23H32N2O3/c26-21(27)17-25-20-11-7-6-10-19(20)23(22(25)28)12-14-24(15-13-23)16-18-8-4-2-1-3-5-9-18/h6-7,10-11,18H,1-5,8-9,12-17H2,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against human opioid receptor mu 1 expressed in HEK293 cells using [3H]DAMGO radioligand				Bioorg Med Chem Lett 15: 5022-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.009 BindingDB Entry DOI: 10.7270/Q2RF5TKC
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