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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50175724'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50175724
PNG
(4-(1-(3-fluorobenzyl)-1H-imidazol-2-yl)-N,4-diphen...)
Show SMILES Fc1cccc(Cn2ccnc2C2(CCN(CC2)C(=O)Nc2ccccc2)c2ccccc2)c1
Show InChI InChI=1S/C28H27FN4O/c29-24-11-7-8-22(20-24)21-33-19-16-30-26(33)28(23-9-3-1-4-10-23)14-17-32(18-15-28)27(34)31-25-12-5-2-6-13-25/h1-13,16,19-20H,14-15,17-18,21H2,(H,31,34)
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PC cid
PC sid
UniChem
Article
PubMed
>4.65E+3n/an/an/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor


Bioorg Med Chem Lett 16: 146-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.025
BindingDB Entry DOI: 10.7270/Q2ZK5G70
More data for this
Ligand-Target Pair