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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50175728'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50175728
PNG
(4-(1-benzyl-1H-imidazol-2-yl)-N-(4-methoxyphenyl)-...)
Show SMILES COc1ccc(NC(=O)N2CCC(CC2)(c2nccn2Cc2ccccc2)c2ccccc2)cc1
Show InChI InChI=1S/C29H30N4O2/c1-35-26-14-12-25(13-15-26)31-28(34)32-19-16-29(17-20-32,24-10-6-3-7-11-24)27-30-18-21-33(27)22-23-8-4-2-5-9-23/h2-15,18,21H,16-17,19-20,22H2,1H3,(H,31,34)
PDB

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>465n/an/an/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor


Bioorg Med Chem Lett 16: 146-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.025
BindingDB Entry DOI: 10.7270/Q2ZK5G70
More data for this
Ligand-Target Pair