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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50175730'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50175730
PNG
(CHEMBL197917 | N,4-diphenyl-4-(1-(pyridin-2-ylmeth...)
Show SMILES O=C(Nc1ccccc1)N1CCC(CC1)(c1nccn1Cc1ccccn1)c1ccccc1
Show InChI InChI=1S/C27H27N5O/c33-26(30-23-11-5-2-6-12-23)31-18-14-27(15-19-31,22-9-3-1-4-10-22)25-29-17-20-32(25)21-24-13-7-8-16-28-24/h1-13,16-17,20H,14-15,18-19,21H2,(H,30,33)
PDB

NCI pathway
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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.42E+3n/an/an/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor


Bioorg Med Chem Lett 16: 146-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.025
BindingDB Entry DOI: 10.7270/Q2ZK5G70
More data for this
Ligand-Target Pair