Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50194272'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50194272 ((+/-)-3-(cyclopropylmethyl)-6-ethyl-1,2,3,4,5,6-he...) Show SMILES CC[C@]12CCN(CC3CC3)C([C@@H]1C)C(=O)c1ccc(cc21)C(=O)NCCc1ccc(cc1)-c1ccccc1 |TLB:14:13:11:5.3.4,6:5:11:15.20.13,THB:19:20:11:5.3.4| Show InChI InChI=1S/C34H38N2O2/c1-3-34-18-20-36(22-25-9-10-25)31(23(34)2)32(37)29-16-15-28(21-30(29)34)33(38)35-19-17-24-11-13-27(14-12-24)26-7-5-4-6-8-26/h4-8,11-16,21,23,25,31H,3,9-10,17-20,22H2,1-2H3,(H,35,38)/t23-,31?,34-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rensselaer Polytechnic Institute Curated by ChEMBL					Assay Description Antagonist activity against human mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS binding				J Med Chem 49: 5635-9 (2006) Article DOI: 10.1021/jm060278n BindingDB Entry DOI: 10.7270/Q208663G
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