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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50273933'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50273933
PNG
((4R*,6aS*,11bR*)-2,3,4,5,6,6a-Hexahydro-3-phenethy...)
Show SMILES Oc1ccc2O[C@@H]3CC[C@H]4C[C@@]3(CCN4CCc3ccccc3)c2c1 |r|
Show InChI InChI=1S/C22H25NO2/c24-18-7-8-20-19(14-18)22-11-13-23(12-10-16-4-2-1-3-5-16)17(15-22)6-9-21(22)25-20/h1-5,7-8,14,17,21,24H,6,9-13,15H2/t17?,21-,22+/m1/s1
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PC cid
PC sid
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Similars

Article
PubMed
352n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism

Curated by ChEMBL


Assay Description
Displacement of [125I]IOXY from human mu opioid receptor expressed in CHO cells coexpressing human recombinant MOR after 2 hrs by liquid scintillatio...


Bioorg Med Chem 19: 4330-7 (2011)


Article DOI: 10.1016/j.bmc.2011.05.035
BindingDB Entry DOI: 10.7270/Q2902452
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50273933
PNG
((4R*,6aS*,11bR*)-2,3,4,5,6,6a-Hexahydro-3-phenethy...)
Show SMILES Oc1ccc2O[C@@H]3CC[C@H]4C[C@@]3(CCN4CCc3ccccc3)c2c1 |r|
Show InChI InChI=1S/C22H25NO2/c24-18-7-8-20-19(14-18)22-11-13-23(12-10-16-4-2-1-3-5-16)17(15-22)6-9-21(22)25-20/h1-5,7-8,14,17,21,24H,6,9-13,15H2/t17?,21-,22+/m1/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
740n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Displacement of [125I]IOXY from human recombinant mu opioid receptor expressed in CHO cells


J Med Chem 51: 7866-81 (2008)


Article DOI: 10.1021/jm800913d
BindingDB Entry DOI: 10.7270/Q2639PM8
More data for this
Ligand-Target Pair