Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50341297'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50341297 (CHEMBL1766035 | N'-(Piperazin-1-yl)-thiazolo[5,4-b...) Show SMILES C(C1CC1)N1CC[C@]23CCCC[C@H]2[C@H]1Cc1cc2sc(NN4CCNCC4)nc2cc31 |r,TLB:0:4:15.30.14:12| Show InChI InChI=1S/C25H35N5S/c1-2-6-25-7-10-29(16-17-4-5-17)22(19(25)3-1)13-18-14-23-21(15-20(18)25)27-24(31-23)28-30-11-8-26-9-12-30/h14-15,17,19,22,26H,1-13,16H2,(H,27,28)/t19-,22+,25+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Agonist activity at human mu opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation counting				J Med Chem 54: 1903-13 (2011) Article DOI: 10.1021/jm101542c BindingDB Entry DOI: 10.7270/Q2028SJ1
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