BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50343255'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50343255
PNG
((2S,4aR,6aR,7R,9S,10aS,10bR)-Methyl 9-acetoxy-2-(8...)
Show SMILES COC(=O)[C@@H]1C[C@H](OC(C)=O)C(=O)[C@H]2[C@@]1(C)CC[C@H]1C(=O)O[C@@H](C[C@]21C)C1=CC2OC1C1C3OC(C21)c1c3c2ccccc2c(=O)c2ccccc12 |r,t:29,TLB:22:26:29:31.35,30:31:33:37.36,34:35:27.26:29,51:36:31.35:33,THB:38:37:31.35:33|
Show InChI InChI=1S/C42H40O10/c1-18(43)49-27-16-25(39(46)48-4)41(2)14-13-24-40(47)51-28(17-42(24,3)38(41)34(27)45)23-15-26-31-32(35(23)50-26)37-30-20-10-6-8-12-22(20)33(44)21-11-7-5-9-19(21)29(30)36(31)52-37/h5-12,15,24-28,31-32,35-38H,13-14,16-17H2,1-4H3/t24-,25-,26?,27-,28-,31?,32?,35?,36?,37?,38-,41-,42-/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>2.70E+3n/an/an/an/an/an/an/an/a



University of Iowa

Curated by ChEMBL


Assay Description
Agonist activity at mu opioid receptor assessed as stimulation of [35S]GTPgammaS binding

J Nat Prod 74: 718-26 (2011)


Article DOI: 10.1021/np1007872
BindingDB Entry DOI: 10.7270/Q2PR7W9V
More data for this
Ligand-Target Pair