BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50398763'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50398763
PNG
(CHEMBL2179657)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35OC(=O)c1ccccc1)-c1ccc(Cl)cc1 |r|
Show InChI InChI=1S/C36H31ClN2O4/c37-27-11-8-22(9-12-27)26-16-25-18-36(43-34(41)23-4-2-1-3-5-23)29-17-24-10-13-28(40)32-30(24)35(36,33(42-32)31(25)38-19-26)14-15-39(29)20-21-6-7-21/h1-5,8-13,16,19,21,29,33,40H,6-7,14-15,17-18,20H2/t29-,33+,35+,36-/m1/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 192n/an/an/an/an/an/an/an/a



Southern Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human mu opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation counting analysis

J Med Chem 55: 8350-63 (2012)


Article DOI: 10.1021/jm300686p
BindingDB Entry DOI: 10.7270/Q2N87BX5
More data for this
Ligand-Target Pair