BindingDB PrimarySearch

Found 11 hits Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM82507'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82507 ((+/-)-Methadone \| CAS_5967-73-7 \| METHADONE \| Meth...) Show SMILES CCC(=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid UniChem Similars	DrugBank PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by PDSP K_i Database									NIDA Res Monogr 178: 440-66 (1998) BindingDB Entry DOI: 10.7270/Q23J3BH2
SRI International Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82507 ((+/-)-Methadone \| CAS_5967-73-7 \| METHADONE \| Meth...) Show SMILES CCC(=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid UniChem Similars	DrugBank Article PubMed	0.720	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by PDSP K_i Database									Mol Pharmacol 45: 330-4 (1994) Article DOI: 10.1016/j.bioorg.2015.02.008 BindingDB Entry DOI: 10.7270/Q21Z42X1
University of Pennsylvania Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM82507 ((+/-)-Methadone \| CAS_5967-73-7 \| METHADONE \| Meth...) Show SMILES CCC(=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid UniChem Similars	PubMed	0.945	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by PDSP K_i Database									J Pharmacol Exp Ther 274: 1263-70 (1995) BindingDB Entry DOI: 10.7270/Q2R20ZVX
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM82507 ((+/-)-Methadone \| CAS_5967-73-7 \| METHADONE \| Meth...) Show SMILES CCC(=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by PDSP K_i Database									NIDA Res Monogr 178: 440-66 (1998) BindingDB Entry DOI: 10.7270/Q23J3BH2
SRI International Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82507 ((+/-)-Methadone \| CAS_5967-73-7 \| METHADONE \| Meth...) Show SMILES CCC(=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid UniChem Similars	DrugBank PubMed	1.45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Memorial Sloan-Kettering Cancer Center Curated by PDSP K_i Database									J Pharmacol Exp Ther 270: 1246-55 (1994) BindingDB Entry DOI: 10.7270/Q2CF9NN9
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM82507 ((+/-)-Methadone \| CAS_5967-73-7 \| METHADONE \| Meth...) Show SMILES CCC(=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid UniChem Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by PDSP K_i Database									J Pharmacol Exp Ther 274: 1263-70 (1995) BindingDB Entry DOI: 10.7270/Q2R20ZVX
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82507 ((+/-)-Methadone \| CAS_5967-73-7 \| METHADONE \| Meth...) Show SMILES CCC(=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid UniChem Similars	DrugBank PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by PDSP K_i Database									J Pharmacol Exp Ther 272: 423-8 (1995) BindingDB Entry DOI: 10.7270/Q2TM78M9
University of Pennsylvania Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82507 ((+/-)-Methadone \| CAS_5967-73-7 \| METHADONE \| Meth...) Show SMILES CCC(=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid UniChem Similars	DrugBank Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK293 cell membrane incubated for 60 mins by radioligand binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00611 BindingDB Entry DOI: 10.7270/Q2N301V5
TBA					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM82507 ((+/-)-Methadone \| CAS_5967-73-7 \| METHADONE \| Meth...) Show SMILES CCC(=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid UniChem Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by PDSP K_i Database									J Pharmacol Exp Ther 272: 423-8 (1995) BindingDB Entry DOI: 10.7270/Q2TM78M9
University of Pennsylvania Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM82507 ((+/-)-Methadone \| CAS_5967-73-7 \| METHADONE \| Meth...) Show SMILES CCC(=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid UniChem Similars	PubMed	19.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by PDSP K_i Database									J Pharmacol Exp Ther 274: 1263-70 (1995) BindingDB Entry DOI: 10.7270/Q2R20ZVX
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82507 ((+/-)-Methadone \| CAS_5967-73-7 \| METHADONE \| Meth...) Show SMILES CCC(=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid UniChem Similars	DrugBank PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
F-59000 Lille Curated by ChEMBL					Assay Description Binding affinity against mu-opiate receptor (human) using [3H]DAMGO radioligand				J Med Chem 44: 3378-90 (2001) BindingDB Entry DOI: 10.7270/Q23X87B8
F-59000 Lille Curated by ChEMBL					More data for this Ligand-Target Pair