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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50003349'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50003349
PNG
(2-Heptyloxy-3-(1-methyl-1,2,5,6-tetrahydro-pyridin...)
Show SMILES CCCCCCCOc1nccnc1C1=CCCN(C)C1 |t:15|
Show InChI InChI=1S/C17H27N3O/c1-3-4-5-6-7-13-21-17-16(18-10-11-19-17)15-9-8-12-20(2)14-15/h9-11H,3-8,12-14H2,1-2H3
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KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a 18n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-oxotremorine-M (Oxo-M) from rat hippocampus muscarinic acetylcholine receptor M1


J Med Chem 35: 4011-9 (1992)


BindingDB Entry DOI: 10.7270/Q2KW5F1K
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50003349
PNG
(2-Heptyloxy-3-(1-methyl-1,2,5,6-tetrahydro-pyridin...)
Show SMILES CCCCCCCOc1nccnc1C1=CCCN(C)C1 |t:15|
Show InChI InChI=1S/C17H27N3O/c1-3-4-5-6-7-13-21-17-16(18-10-11-19-17)15-9-8-12-20(2)14-15/h9-11H,3-8,12-14H2,1-2H3
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a 5.10E+3n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Efficacy at muscarinic acetylcholine receptor M1 measured by the ability to inhibit the electrically stimulated twitch of the rabbit vas deferens


J Med Chem 35: 4011-9 (1992)


BindingDB Entry DOI: 10.7270/Q2KW5F1K
More data for this
Ligand-Target Pair