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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50326225'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50326225
PNG
(CHEMBL1243357 | N-{1-[3-(6-Fluoro-2-oxo-3,4-dihydr...)
Show SMILES CCC(=O)NC1CCN(CCCN2C(=O)CCc3cc(F)ccc23)CC1
Show InChI InChI=1S/C20H28FN3O2/c1-2-19(25)22-17-8-12-23(13-9-17)10-3-11-24-18-6-5-16(21)14-15(18)4-7-20(24)26/h5-6,14,17H,2-4,7-13H2,1H3,(H,22,25)
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Similars
Article
PubMed
n/an/an/an/a 9n/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assay

J Med Chem 53: 6386-97 (2010)


Article DOI: 10.1021/jm100697g
BindingDB Entry DOI: 10.7270/Q2765G9K
More data for this
Ligand-Target Pair