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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50326228'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50326228
PNG
(CHEMBL1243387 | N-{1-[3-(6,7-Difluoro-2-oxo-3,4-di...)
Show SMILES CCC(=O)NC1CCN(CCCN2C(=O)CCc3cc(F)c(F)cc23)CC1
Show InChI InChI=1S/C20H27F2N3O2/c1-2-19(26)23-15-6-10-24(11-7-15)8-3-9-25-18-13-17(22)16(21)12-14(18)4-5-20(25)27/h12-13,15H,2-11H2,1H3,(H,23,26)
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Similars
Article
PubMed
n/an/an/an/a 20n/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assay

J Med Chem 53: 6386-97 (2010)


Article DOI: 10.1021/jm100697g
BindingDB Entry DOI: 10.7270/Q2765G9K
More data for this
Ligand-Target Pair