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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50326230'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50326230
PNG
(CHEMBL1242925 | N-{1-[3-(6,7-Difluoro-3-oxo-2,3-di...)
Show SMILES CCC(=O)NC1CCN(CCCN2C(=O)COc3cc(F)c(F)cc23)CC1
Show InChI InChI=1S/C19H25F2N3O3/c1-2-18(25)22-13-4-8-23(9-5-13)6-3-7-24-16-10-14(20)15(21)11-17(16)27-12-19(24)26/h10-11,13H,2-9,12H2,1H3,(H,22,25)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 10n/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assay

J Med Chem 53: 6386-97 (2010)


Article DOI: 10.1021/jm100697g
BindingDB Entry DOI: 10.7270/Q2765G9K
More data for this
Ligand-Target Pair