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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50326231'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50326231
PNG
(CHEMBL1242951 | N-{1-[3-(6,7-Difluoro-2-oxo-3,4-di...)
Show SMILES Fc1cc2CCC(=O)N(CCCN3CCC(CC3)NC(=O)Cc3ccccc3)c2cc1F
Show InChI InChI=1S/C25H29F2N3O2/c26-21-16-19-7-8-25(32)30(23(19)17-22(21)27)12-4-11-29-13-9-20(10-14-29)28-24(31)15-18-5-2-1-3-6-18/h1-3,5-6,16-17,20H,4,7-15H2,(H,28,31)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 15n/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assay

J Med Chem 53: 6386-97 (2010)


Article DOI: 10.1021/jm100697g
BindingDB Entry DOI: 10.7270/Q2765G9K
More data for this
Ligand-Target Pair