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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50326236'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50326236
PNG
(CHEMBL1243074 | N-{1-[3-(8-Fluoro-2-oxo-3,4-dihydr...)
Show SMILES Fc1cccc2CCC(=O)N(CCCN3CCC(CC3)NC(=O)Cc3ccccc3)c12
Show InChI InChI=1S/C25H30FN3O2/c26-22-9-4-8-20-10-11-24(31)29(25(20)22)15-5-14-28-16-12-21(13-17-28)27-23(30)18-19-6-2-1-3-7-19/h1-4,6-9,21H,5,10-18H2,(H,27,30)
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Similars
Article
PubMed
n/an/an/an/a 290n/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assay

J Med Chem 53: 6386-97 (2010)


Article DOI: 10.1021/jm100697g
BindingDB Entry DOI: 10.7270/Q2765G9K
More data for this
Ligand-Target Pair