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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50326241'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50326241
PNG
(CHEMBL1243139 | N-(1-(3-(2-oxobenzo[d]oxazol-3(2H)...)
Show SMILES O=C(Cc1ccccc1)NC1CCN(CCCn2c3ccccc3oc2=O)CC1
Show InChI InChI=1S/C23H27N3O3/c27-22(17-18-7-2-1-3-8-18)24-19-11-15-25(16-12-19)13-6-14-26-20-9-4-5-10-21(20)29-23(26)28/h1-5,7-10,19H,6,11-17H2,(H,24,27)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.10E+3n/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assay

J Med Chem 53: 6386-97 (2010)


Article DOI: 10.1021/jm100697g
BindingDB Entry DOI: 10.7270/Q2765G9K
More data for this
Ligand-Target Pair