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Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50362387'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50362387
PNG
(CHEMBL1940119)
Show SMILES Clc1ccc2nonc2c1S(=O)(=O)NCCC(=O)N1CCN(CC1)c1ccc(Br)cn1
Show InChI InChI=1S/C18H18BrClN6O4S/c19-12-1-4-15(21-11-12)25-7-9-26(10-8-25)16(27)5-6-22-31(28,29)18-13(20)2-3-14-17(18)24-30-23-14/h1-4,11,22H,5-10H2
UniProtKB/SwissProt

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Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by fl...

Bioorg Med Chem Lett 22: 1044-8 (2012)


Article DOI: 10.1016/j.bmcl.2011.11.110
BindingDB Entry DOI: 10.7270/Q2XS5VVC
More data for this
Ligand-Target Pair