Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M2' and Ligand = 'BDBM50018291'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50018291 (11-{2-[2-(3-Diethylamino-propyl)-piperidin-1-yl]-a...) Show SMILES CCN(CC)CCCC1CCCCN1CC(=O)N1c2ccccc2C(=O)Nc2cccnc12 Show InChI InChI=1S/C26H35N5O2/c1-3-29(4-2)17-10-12-20-11-7-8-18-30(20)19-24(32)31-23-15-6-5-13-21(23)26(33)28-22-14-9-16-27-25(22)31/h5-6,9,13-16,20H,3-4,7-8,10-12,17-19H2,1-2H3,(H,28,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
College of Pharmacy Curated by ChEMBL					Assay Description Inhibition of muscarinic (M2) receptor isolated from rat atria				J Med Chem 37: 3775-88 (1994) BindingDB Entry DOI: 10.7270/Q2QC02JX
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50018291 (11-{2-[2-(3-Diethylamino-propyl)-piperidin-1-yl]-a...) Show SMILES CCN(CC)CCCC1CCCCN1CC(=O)N1c2ccccc2C(=O)Nc2cccnc12 Show InChI InChI=1S/C26H35N5O2/c1-3-29(4-2)17-10-12-20-11-7-8-18-30(20)19-24(32)31-23-15-6-5-13-21(23)26(33)28-22-14-9-16-27-25(22)31/h5-6,9,13-16,20H,3-4,7-8,10-12,17-19H2,1-2H3,(H,28,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Karl Thomae GmbH Curated by ChEMBL					Assay Description Binding affinity to the rat cardiac muscarinic acetylcholine receptor M2 using 0.3 nM [3H]-N-methylscopolamine as radioligand				J Med Chem 32: 1718-24 (1989) BindingDB Entry DOI: 10.7270/Q2XG9Q4Q
					More data for this Ligand-Target Pair