Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M2' and Ligand = 'BDBM50077548'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50077548 (1-{4-[3-(4-Fluoro-phenyl)-prop-2-ynyloxy]-[1,2,5]t...) Show SMILES Fc1ccc(cc1)C#CCOc1nsnc1C12CN3CC1C2C3 Show InChI InChI=1S/C17H14FN3OS/c18-12-5-3-11(4-6-12)2-1-7-22-16-15(19-23-20-16)17-10-21-8-13(17)14(17)9-21/h3-6,13-14H,7-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of [3H]- Oxo-M binding at Muscarinic acetylcholine receptor M2 in rat brain membranes.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50077548 (1-{4-[3-(4-Fluoro-phenyl)-prop-2-ynyloxy]-[1,2,5]t...) Show SMILES Fc1ccc(cc1)C#CCOc1nsnc1C12CN3CC1C2C3 Show InChI InChI=1S/C17H14FN3OS/c18-12-5-3-11(4-6-12)2-1-7-22-16-15(19-23-20-16)17-10-21-8-13(17)14(17)9-21/h3-6,13-14H,7-10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	791	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested for its potency at M-2 receptor by inhibiting forskolin induced c-AMP formation in CHO-M2 cells human M2 receptor				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
					More data for this Ligand-Target Pair