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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M2' and Ligand = 'BDBM50291591'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M2


(RAT)		BDBM50291591
PNG
(1'-(4-diethylamino-2-butynyl)spiro[10,11-dihydro-5...)
Show SMILES CCN(CC)CC#CCN1C(=O)CC2(C1=O)c1ccccc1CCc1ccccc21
Show InChI InChI=1S/C26H28N2O2/c1-3-27(4-2)17-9-10-18-28-24(29)19-26(25(28)30)22-13-7-5-11-20(22)15-16-21-12-6-8-14-23(21)26/h5-8,11-14H,3-4,15-19H2,1-2H3
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UniChem
Article
 2.09E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]QNB (quinuclidinyl benzylate) from muscarinic M2 receptor of rat heart homogenates.

Bioorg Med Chem Lett 7: 979-984 (1997)


Article DOI: 10.1016/S0960-894X(97)00143-1
BindingDB Entry DOI: 10.7270/Q2N29XFM
More data for this
Ligand-Target Pair