Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M2' and Ligand = 'BDBM50413132'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50413132 (CHEMBL554918) Show SMILES CCOC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(cc2)C(=O)c2ccccc2)C(=O)N[C@H]2CC[N+](C)(Cc3ccc4OCOc4c3)C2)cc1 |r| Show InChI InChI=1S/C39H40N4O7/c1-3-48-38(46)30-14-16-31(17-15-30)41-39(47)42-33(21-26-9-12-29(13-10-26)36(44)28-7-5-4-6-8-28)37(45)40-32-19-20-43(2,24-32)23-27-11-18-34-35(22-27)50-25-49-34/h4-18,22,32-33H,3,19-21,23-25H2,1-2H3,(H2-,40,41,42,45,46,47)/p+1/t32-,33-,43?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.51	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant muscarinic M2 receptor expressed in CHO cells coexpressing chimeric G protein Gqi5 assessed as inhibition of...				Bioorg Med Chem Lett 18: 5481-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.020 BindingDB Entry DOI: 10.7270/Q23B61CM
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