Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM50267470'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50267470 (3-[Hydroxy(diphenyl)methyl]-1-(2-phenylethyl)-1-az...) Show SMILES OC(C1C[N+]2(CCc3ccccc3)CCC1CC2)(c1ccccc1)c1ccccc1 |(10.91,-21.64,;10.13,-22.98,;8.8,-22.2,;8.8,-20.65,;7.46,-19.87,;7.44,-18.33,;8.77,-17.55,;8.75,-16.01,;10.08,-15.23,;10.07,-13.69,;8.72,-12.93,;7.39,-13.72,;7.41,-15.26,;6.12,-20.65,;6.12,-22.2,;7.46,-22.97,;8.11,-21.68,;6.82,-21.05,;9.37,-24.32,;7.83,-24.32,;7.07,-25.65,;7.85,-26.99,;9.4,-26.97,;10.15,-25.63,;11.46,-23.75,;11.45,-25.28,;12.77,-26.05,;14.1,-25.28,;14.1,-23.75,;12.78,-22.99,)| Show InChI InChI=1S/C28H32NO/c30-28(25-12-6-2-7-13-25,26-14-8-3-9-15-26)27-22-29(20-17-24(27)18-21-29)19-16-23-10-4-1-5-11-23/h1-15,24,27,30H,16-22H2/q+1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.82E+6	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human cloned muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilizatio...				J Med Chem 52: 2493-505 (2009) Article DOI: 10.1021/jm801601v BindingDB Entry DOI: 10.7270/Q2H131X8
					More data for this Ligand-Target Pair