Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM50267647'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50267647 (4-[Hydroxy(diphenyl)methyl]-1-[5-(phenyloxy)pentyl...) Show SMILES OC(c1ccccc1)(c1ccccc1)C12CC[N+](CCCCCOc3ccccc3)(CC1)CC2 Show InChI InChI=1S/C31H38NO2/c33-31(27-13-5-1-6-14-27,28-15-7-2-8-16-28)30-19-23-32(24-20-30,25-21-30)22-11-4-12-26-34-29-17-9-3-10-18-29/h1-3,5-10,13-18,33H,4,11-12,19-26H2/q+1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.06E+5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human cloned muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilizatio...				J Med Chem 52: 2493-505 (2009) Article DOI: 10.1021/jm801601v BindingDB Entry DOI: 10.7270/Q2H131X8
					More data for this Ligand-Target Pair