Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM50345678'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50345678 (1-(endo-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)-2-...) Show SMILES CCC(O)(CC1C[C@H]2CC[C@H](C1)N2C)c1ccccc1 |r,TLB:13:12:5.6.11:8.9,4:5:12:8.9| Show InChI InChI=1S/C18H27NO/c1-3-18(20,15-7-5-4-6-8-15)13-14-11-16-9-10-17(12-14)19(16)2/h4-8,14,16-17,20H,3,9-13H2,1-2H3/t16-,17-,18?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	135	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by FLIPR				J Med Chem 52: 5241-52 (2010) Article DOI: 10.1021/jm900736e BindingDB Entry DOI: 10.7270/Q2PK0H54
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