Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human)) | BDBM50396483 (PLX-4032 | RG 7204 | Ro 5185426 | US10570155, Vemu...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a |
ACADIA PHARMACEUTICALS INC.; ALLERGAN, INC. US Patent | Assay Description NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ... | US Patent US9670209 (2017) BindingDB Entry DOI: 10.7270/Q2MS3QX2 | |||||||||||
More data for this Ligand-Target Pair |