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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M4' and Ligand = 'BDBM50194655'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M4


(Homo sapiens (Human))		BDBM50194655
PNG
((2R)-N-(1-cyclopentyl-4-piperidinylmethyl)-1-((2S,...)
Show SMILES O[C@@H]1C[C@H](N(C1)C(=O)CC(c1ccc(F)cc1)(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1CCC[C@@H]1C(=O)NCC1CCN(CC1)C1CCCC1
Show InChI InChI=1S/C42H49F3N4O4/c43-32-13-7-29(8-14-32)42(30-9-15-33(44)16-10-30,31-11-17-34(45)18-12-31)25-39(51)49-27-36(50)24-38(49)41(53)48-21-3-6-37(48)40(52)46-26-28-19-22-47(23-20-28)35-4-1-2-5-35/h7-18,28,35-38,50H,1-6,19-27H2,(H,46,52)/t36-,37-,38+/m1/s1
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Similars
Article
PubMed
 48n/an/an/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]NMS binding to human cloned M4 receptor expressed in CHO cells

J Med Chem 49: 5653-63 (2006)


Article DOI: 10.1021/jm051205r
BindingDB Entry DOI: 10.7270/Q2F76C6K
More data for this
Ligand-Target Pair