Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M4' and Ligand = 'BDBM50240549'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50240549 (CHEMBL4099192) Show SMILES O=C(C1CCN(CC1)c1cc(Oc2ccc3OCOc3c2)ncn1)N1CCc2ccccc2C1 Show InChI InChI=1S/C26H26N4O4/c31-26(30-12-7-18-3-1-2-4-20(18)15-30)19-8-10-29(11-9-19)24-14-25(28-16-27-24)34-21-5-6-22-23(13-21)33-17-32-22/h1-6,13-14,16,19H,7-12,15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Antagonist activity at recombinant human M4 receptor expressed in CHO cells co-expressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 27: 2479-2483 (2017) Article DOI: 10.1016/j.bmcl.2017.04.009 BindingDB Entry DOI: 10.7270/Q2VT1V7H
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50240549 (CHEMBL4099192) Show SMILES O=C(C1CCN(CC1)c1cc(Oc2ccc3OCOc3c2)ncn1)N1CCc2ccccc2C1 Show InChI InChI=1S/C26H26N4O4/c31-26(30-12-7-18-3-1-2-4-20(18)15-30)19-8-10-29(11-9-19)24-14-25(28-16-27-24)34-21-5-6-22-23(13-21)33-17-32-22/h1-6,13-14,16,19H,7-12,15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Antagonist activity at recombinant human M4 receptor expressed in CHO cells co-expressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 27: 2479-2483 (2017) Article DOI: 10.1016/j.bmcl.2017.04.009 BindingDB Entry DOI: 10.7270/Q2VT1V7H
					More data for this Ligand-Target Pair