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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'N-acetyl-beta-D-glucosaminidase (O-GlcNAcase)' and Ligand = 'BDBM179374'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
N-acetyl-beta-D-glucosaminidase (O-GlcNAcase)


(Homo sapiens (Human))
BDBM179374
PNG
(US9126957, 10)
Show SMILES C[C@@H](O)[C@@H]1C[C@H]2SC(=N[C@H]2[C@H](O)[C@H]1O)N(C)C |c:7|
Show InChI InChI=1S/C11H20N2O3S/c1-5(14)6-4-7-8(10(16)9(6)15)12-11(17-7)13(2)3/h5-10,14-16H,4H2,1-3H3/t5-,6+,7-,8-,9+,10+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.140 -56.2n/an/an/an/an/a7.025



MERCK SHARP & DOHME CORP.; ALECTOS THERAPEUTICS, INC.

US Patent


Assay Description
Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...


US Patent US9126957 (2015)


BindingDB Entry DOI: 10.7270/Q2DV1HN2
More data for this
Ligand-Target Pair