Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'N-acetyltransferase Eis' and Ligand = 'BDBM349595'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-acetyltransferase Eis (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM349595 (US10208000, Compound 37) Show SMILES CN(c1cccc(F)c1)S(=O)(=O)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 Show InChI InChI=1S/C15H12FN3O4S/c1-19(10-4-2-3-9(16)7-10)24(22,23)11-5-6-12-13(8-11)18-15(21)14(20)17-12/h2-8H,1H3,(H,17,20)(H,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Research Foundation US Patent					Assay Description To investigate the potential of these compounds as Eis inhibitors for use in combination with KAN, their biochemical (IC50 values against purified Ei...				US Patent US10208000 (2019) BindingDB Entry DOI: 10.7270/Q28S4S2Z
					More data for this Ligand-Target Pair