Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'N-formyl peptide receptor 2' and Ligand = 'BDBM21692'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM21692 (1-(4-chlorophenyl)-3-[1-methyl-3-oxo-2-phenyl-5-(p...) Show SMILES CC(C)c1c(NC(=O)Nc2ccc(Cl)cc2)c(=O)n(-c2ccccc2)n1C Show InChI InChI=1S/C20H21ClN4O2/c1-13(2)18-17(23-20(27)22-15-11-9-14(21)10-12-15)19(26)25(24(18)3)16-7-5-4-6-8-16/h4-13H,1-3H3,(H2,22,23,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	44	n/a	n/a	7.2	37
Amgen					Assay Description hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...				Bioorg Med Chem Lett 17: 6633-7 (2007) Article DOI: 10.1016/j.bmcl.2007.09.043 BindingDB Entry DOI: 10.7270/Q25H7DJ4
					More data for this Ligand-Target Pair				3D Structure (crystal)
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM21692 (1-(4-chlorophenyl)-3-[1-methyl-3-oxo-2-phenyl-5-(p...) Show SMILES CC(C)c1c(NC(=O)Nc2ccc(Cl)cc2)c(=O)n(-c2ccccc2)n1C Show InChI InChI=1S/C20H21ClN4O2/c1-13(2)18-17(23-20(27)22-15-11-9-14(21)10-12-15)19(26)25(24(18)3)16-7-5-4-6-8-16/h4-13H,1-3H3,(H2,22,23,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	41	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR2 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair				3D Structure (crystal)
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM21692 (1-(4-chlorophenyl)-3-[1-methyl-3-oxo-2-phenyl-5-(p...) Show SMILES CC(C)c1c(NC(=O)Nc2ccc(Cl)cc2)c(=O)n(-c2ccccc2)n1C Show InChI InChI=1S/C20H21ClN4O2/c1-13(2)18-17(23-20(27)22-15-11-9-14(21)10-12-15)19(26)25(24(18)3)16-7-5-4-6-8-16/h4-13H,1-3H3,(H2,22,23,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	95	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Biased agonist activity at human FPR2 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...				J Med Chem 62: 5242-5248 (2019) Article DOI: 10.1021/acs.jmedchem.8b01912 BindingDB Entry DOI: 10.7270/Q2W0998D
					More data for this Ligand-Target Pair				3D Structure (crystal)
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM21692 (1-(4-chlorophenyl)-3-[1-methyl-3-oxo-2-phenyl-5-(p...) Show SMILES CC(C)c1c(NC(=O)Nc2ccc(Cl)cc2)c(=O)n(-c2ccccc2)n1C Show InChI InChI=1S/C20H21ClN4O2/c1-13(2)18-17(23-20(27)22-15-11-9-14(21)10-12-15)19(26)25(24(18)3)16-7-5-4-6-8-16/h4-13H,1-3H3,(H2,22,23,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	44	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Activity at human FPRL1-mediated calcium mobilization in CHO cells				Bioorg Med Chem Lett 16: 3713-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.068 BindingDB Entry DOI: 10.7270/Q2DF6QTJ
					More data for this Ligand-Target Pair				3D Structure (crystal)