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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'N-formyl peptide receptor 2' and Ligand = 'BDBM50098184'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50098184
PNG
(AG-26 | CHEMBL1289260)
Show SMILES COc1ccc(CCNC(=O)Nc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C19H32N2O/c1-14(2)17-11-16(13-21-7-9-22-10-8-21)12-18(15(3)4)19(17)20(5)6/h11-12,14-15H,7-10,13H2,1-6H3
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KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 990n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50098184
PNG
(AG-26 | CHEMBL1289260)
Show SMILES COc1ccc(CCNC(=O)Nc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C19H32N2O/c1-14(2)17-11-16(13-21-7-9-22-10-8-21)12-18(15(3)4)19(17)20(5)6/h11-12,14-15H,7-10,13H2,1-6H3
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 400n/an/an/an/a



University of Warsaw

Curated by ChEMBL


Assay Description
Agonist activity against human FPR2 expressed in human HL60 cells by Fluo-4AM dye based intracellular Ca2+ mobilization assay


Bioorg Med Chem 23: 4072-81 (2015)


Article DOI: 10.1016/j.bmc.2015.03.062
BindingDB Entry DOI: 10.7270/Q2KD20PR
More data for this
Ligand-Target Pair