Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'NAD-dependent histone deacetylase SIR2' and Ligand = 'BDBM50146057'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae)	BDBM50146057 (CHEMBL313262 | N,N-Diethyl-3-(2-hydroxy-naphthalen...) Show SMILES CCN(CC)C(=O)CCc1c(O)ccc2ccccc12 Show InChI InChI=1S/C17H21NO2/c1-3-18(4-2)17(20)12-10-15-14-8-6-5-7-13(14)9-11-16(15)19/h5-9,11,19H,3-4,10,12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
Fred Hutchinson Cancer Research Center Curated by ChEMBL					Assay Description In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates				J Med Chem 47: 2635-44 (2004) Article DOI: 10.1021/jm030473r BindingDB Entry DOI: 10.7270/Q228071B
					More data for this Ligand-Target Pair