Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NAD-dependent histone deacetylase SIR2 (Saccharomyces cerevisiae) | BDBM50177985 (CHEMBL200762 | meta-Sirtinol) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL | Assay Description Inhibitory activity against recombinant yeast Sir2 | J Med Chem 48: 7789-95 (2005) Article DOI: 10.1021/jm050100l BindingDB Entry DOI: 10.7270/Q26M36DP | |||||||||||
More data for this Ligand-Target Pair |