Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'NADPH oxidase 4' and Ligand = 'BDBM50330701'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NADPH oxidase 4 (Homo sapiens (Human))	BDBM50330701 (1-(2-(3-methoxyphenyl)acetyl)-4-methyl-2-phenyl-5-...) Show SMILES COc1cccc(CC(=O)n2n(-c3ccccc3)c(=O)c3c(C)n(Cc4cccnc4)c(=O)cc23)c1 Show InChI InChI=1S/C28H24N4O4/c1-19-27-24(16-25(33)30(19)18-21-9-7-13-29-17-21)32(31(28(27)35)22-10-4-3-5-11-22)26(34)15-20-8-6-12-23(14-20)36-2/h3-14,16-17H,15,18H2,1-2H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	285	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genkyotex, S.A. Curated by ChEMBL					Assay Description Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPH				J Med Chem 53: 7715-30 (2010) Article DOI: 10.1021/jm100773e BindingDB Entry DOI: 10.7270/Q2KH0NKJ
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