BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'NADPH oxidase 4' and Ligand = 'BDBM50330728'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
NADPH oxidase 4


(Homo sapiens (Human))		BDBM50330728
PNG
(2-(2-(4-chlorophenoxy)ethyl)-4-methyl-5-(pyridin-2...)
Show SMILES Cc1n(Cc2ccccn2)c(=O)cc2[nH]n(CCOc3ccc(Cl)cc3)c(=O)c12
Show InChI InChI=1S/C21H19ClN4O3/c1-14-20-18(12-19(27)25(14)13-16-4-2-3-9-23-16)24-26(21(20)28)10-11-29-17-7-5-15(22)6-8-17/h2-9,12,24H,10-11,13H2,1H3
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 326n/an/an/an/an/an/an/an/a



Genkyotex, S.A.

Curated by ChEMBL


Assay Description
Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPH

J Med Chem 53: 7715-30 (2010)


Article DOI: 10.1021/jm100773e
BindingDB Entry DOI: 10.7270/Q2KH0NKJ
More data for this
Ligand-Target Pair