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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'NADPH oxidase 4' and Ligand = 'BDBM50330731'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
NADPH oxidase 4


(Homo sapiens (Human))		BDBM50330731
PNG
(2-(2-chloro-4-fluorobenzyl)-4-methyl-5-(pyridin-2-...)
Show SMILES Cc1n(Cc2ccccn2)c(=O)cc2[nH]n(Cc3ccc(F)cc3Cl)c(=O)c12
Show InChI InChI=1S/C20H16ClFN4O2/c1-12-19-17(9-18(27)25(12)11-15-4-2-3-7-23-15)24-26(20(19)28)10-13-5-6-14(22)8-16(13)21/h2-9,24H,10-11H2,1H3
KEGG

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Patents

Similars
Article
PubMed
 342n/an/an/an/an/an/an/an/a



Genkyotex, S.A.

Curated by ChEMBL


Assay Description
Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPH

J Med Chem 53: 7715-30 (2010)


Article DOI: 10.1021/jm100773e
BindingDB Entry DOI: 10.7270/Q2KH0NKJ
More data for this
Ligand-Target Pair