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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'NT-3 growth factor receptor' and Ligand = 'BDBM50092096'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
NT-3 growth factor receptor


(Homo sapiens (Human))
BDBM50092096
PNG
(CHEMBL3582430)
Show SMILES COc1ccccc1CNc1ccc2ncc(-c3ccc(cc3)C#N)n2n1
Show InChI InChI=1S/C22H34N8O7/c1-37-13-6-4-12(5-7-13)9-15(19(24)34)30-21(36)16(10-18(32)33)29-17(31)11-28-20(35)14(23)3-2-8-27-22(25)26/h4-7,14-16H,2-3,8-11,23H2,1H3,(H2,24,34)(H,28,35)(H,29,31)(H,30,36)(H,32,33)(H4,25,26,27)/t14?,15-,16-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 75n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibition of Tel-fused TRKC (unknown origin) overexpressed in mouse BA/F3 cells assessed as inhibition of cell proliferation after 48 hrs by lucifer...


ACS Med Chem Lett 6: 562-7 (2015)


Article DOI: 10.1021/acsmedchemlett.5b00050
BindingDB Entry DOI: 10.7270/Q2TM7CW4
More data for this
Ligand-Target Pair