Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM298291'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM298291 (US10123984, Example 2N | US11547687, Example 2N | ...) Show SMILES N[C@@H](C[C@@H](O)C(=O)OCc1ccccc1)Cc1ccc(cc1)-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C24H24ClNO3/c25-21-8-4-7-20(14-21)19-11-9-17(10-12-19)13-22(26)15-23(27)24(28)29-16-18-5-2-1-3-6-18/h1-12,14,22-23,27H,13,15-16,26H2/t22-,23-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
THERAVANCE BIOPHARMA R&D IP, LLC US Patent					Assay Description The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...				US Patent US10123984 (2018) BindingDB Entry DOI: 10.7270/Q2KK9DVB
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