Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM298319'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM298319 (US10123984, Example 11-4 | US10744104, Example 11-...) Show SMILES CC(C)COC(=O)C(=O)N[C@H](Cc1ccc(cc1)-c1cccc(Cl)c1)C[C@@](C)(CO)C(O)=O |r| Show InChI InChI=1S/C25H30ClNO6/c1-16(2)14-33-23(30)22(29)27-21(13-25(3,15-28)24(31)32)11-17-7-9-18(10-8-17)19-5-4-6-20(26)12-19/h4-10,12,16,21,28H,11,13-15H2,1-3H3,(H,27,29)(H,31,32)/t21-,25+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Theravance Biopharma R&D IP, LLC US Patent					Assay Description The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...				US Patent US10744104 (2020) BindingDB Entry DOI: 10.7270/Q2PG1VT4
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM298319 (US10123984, Example 11-4 | US10744104, Example 11-...) Show SMILES CC(C)COC(=O)C(=O)N[C@H](Cc1ccc(cc1)-c1cccc(Cl)c1)C[C@@](C)(CO)C(O)=O |r| Show InChI InChI=1S/C25H30ClNO6/c1-16(2)14-33-23(30)22(29)27-21(13-25(3,15-28)24(31)32)11-17-7-9-18(10-8-17)19-5-4-6-20(26)12-19/h4-10,12,16,21,28H,11,13-15H2,1-3H3,(H,27,29)(H,31,32)/t21-,25+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
THERAVANCE BIOPHARMA R&D IP, LLC US Patent					Assay Description The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...				US Patent US10123984 (2018) BindingDB Entry DOI: 10.7270/Q2KK9DVB
					More data for this Ligand-Target Pair