Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM300278'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM300278 (US9593110, 18-11) Show SMILES COc1cnc(o1)C(=O)N[C@@H](C[C@@H](N)C(O)=O)Cc1ccc(cc1Cl)-c1cc(Cl)ccc1F Show InChI InChI=1S/C22H20Cl2FN3O5/c1-32-19-10-27-21(33-19)20(29)28-14(9-18(26)22(30)31)6-12-3-2-11(7-16(12)24)15-8-13(23)4-5-17(15)25/h2-5,7-8,10,14,18H,6,9,26H2,1H3,(H,28,29)(H,30,31)/t14-,18-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Theravence Biopharma R&D IP, LLC US Patent					Assay Description Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...				US Patent US9593110 (2017) BindingDB Entry DOI: 10.7270/Q2MC9224
					More data for this Ligand-Target Pair