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Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50016765'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Oryctolagus cuniculus (rabbit))		BDBM50016765
PNG
(2-[1-(2-Carboxy-ethylcarbamoyl)-2-phenyl-ethylamin...)
Show SMILES OC(=O)CCNC(=O)[C@H](Cc1ccccc1)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C21H24N2O5/c24-19(25)11-12-22-20(26)17(13-15-7-3-1-4-8-15)23-18(21(27)28)14-16-9-5-2-6-10-16/h1-10,17-18,23H,11-14H2,(H,22,26)(H,24,25)(H,27,28)/t17-,18-/m0/s1
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n/an/a 20n/an/an/an/an/an/a



Schering-Plough Research

Curated by ChEMBL


Assay Description
Compound was evaluated for the ability to inhibit neutral endopeptidase purified from rabbit kidney

J Med Chem 32: 737-9 (1989)


BindingDB Entry DOI: 10.7270/Q2BV7FMF
More data for this
Ligand-Target Pair