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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50016769'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Oryctolagus cuniculus (rabbit))		BDBM50016769
PNG
(2-[1-(2-Carboxy-ethylcarbamoyl)-2-phenyl-ethylamin...)
Show SMILES OC(=O)CCNC(=O)[C@H](Cc1ccccc1)N[C@@H](CCc1ccccc1)C(O)=O
Show InChI InChI=1S/C22H26N2O5/c25-20(26)13-14-23-21(27)19(15-17-9-5-2-6-10-17)24-18(22(28)29)12-11-16-7-3-1-4-8-16/h1-10,18-19,24H,11-15H2,(H,23,27)(H,25,26)(H,28,29)/t18-,19-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 16n/an/an/an/an/an/a



Schering-Plough Research

Curated by ChEMBL


Assay Description
Compound was evaluated for the ability to inhibit neutral endopeptidase purified from rabbit kidney

J Med Chem 32: 737-9 (1989)


BindingDB Entry DOI: 10.7270/Q2BV7FMF
More data for this
Ligand-Target Pair