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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50039506'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Oryctolagus cuniculus (rabbit))		BDBM50039506
PNG
((S)-3-tert-Butylsulfanyl-2-((S)-2-mercaptomethyl-3...)
Show SMILES CC(C)(C)SC[C@@H](NC(=O)[C@@H](CS)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C17H25NO3S2/c1-17(2,3)23-11-14(16(20)21)18-15(19)13(10-22)9-12-7-5-4-6-8-12/h4-8,13-14,22H,9-11H2,1-3H3,(H,18,19)(H,20,21)/t13-,14-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 49n/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against neutral endopeptidase (NEP)

J Med Chem 37: 2461-76 (1994)


BindingDB Entry DOI: 10.7270/Q2571B20
More data for this
Ligand-Target Pair